2 760份临床标本细菌培养结果与药敏分析

目的总结我院2006年6月￣12月2760份临床标本的培养结果及药敏状况,以指导临床合理使用抗生素。方法对临床送检2760份标本中分离出的634株病原菌分类、药敏试验结果进行回顾性分析。结果634株病原菌中革兰阳性菌113株,占17.8%,革兰阴性菌395株,占62.3%,真菌126株,占19.3%。大肠埃希菌、绿脓假单胞菌、白色念珠菌、鲍曼不动杆菌、金黄色葡萄球菌为主要细菌,感染部位以呼吸道、血液、泌尿道、皮肤软组织为多。常见G 、G-菌的耐药性有上升趋势,且具有多重耐药性。结论治疗感染性疾病时应进行病原学检查,依据药敏试验结果合理使用抗生素,以减少耐药菌株产生。

Analysis of bacteria culture of 2 760 clinical specimens and their drug sensitivity test

Objective To investigate the composition of pathogenic bacteria in the past half years and the antimicrobialresistance of these bacteria,and to guide the clinical treatment.Methods A total of 6 2760 samples were detected in the past half year,Species identification and antibiotic resistance tests were performed by the VITEK automicroscan systems.Results 634 stratus were isolated f rom 2760 samples,Positive rate was 23.0 %. Gram-positive microorganisms accounted for 17.8 %(113) of the positive culture results,Gram-negative microorganisms accounted for 62.3 % (395), and fungi accounted for19.3 %(126).The main pathogens were Escherichia coli , Pseudomonas aeruginosa, Candida albicans, Acinetobacter baumannii and Staphylococcus aureus. The infection appeared at respiratory tract , blood, urinary tract and skin frequently. The drug resistance rate was increasing and some bacteria were multi drug resistance strains.Conclusion In order to reduce drug resistance strains,it is important that bacterial culture should be carry out actively and antibiotics must be based on the drug sensitivity test. of clinical significance to administerantibiotics based on drug sensitivity test.