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连芙胃和口服液联合奥美拉唑和阿莫西林治疗幽门螺杆菌感染的临床研究
引用本文:潘洁露,林江,朱梅萍,陆美华. 连芙胃和口服液联合奥美拉唑和阿莫西林治疗幽门螺杆菌感染的临床研究[J]. 中国中西医结合消化杂志, 2011, 19(6): 362-365
作者姓名:潘洁露  林江  朱梅萍  陆美华
作者单位:上海中医药大学附属曙光医院消化科,上海,200021
基金项目:上海市卫生局科研基金资助项目,上海市教委重点学科项目
摘    要:[目的]观察连芙胃和口服液联合奥美拉唑和阿莫西林治疗幽门螺杆菌(H.pylori,Hp)感染的临床疗效、安全性和成本效果。[方法]86例Hp感染患者随机分为2组,试验组42例,予连芙胃和口服液20ml加奥美拉唑20mg加阿莫西林l.0g,2次/d;对照组44例,予奥美拉唑20mg加阿莫西林1.0g加克拉霉素500mg,2次/d口服;疗程均为1周。观察主要疗效指标Hp根除率;次要疗效指标临床症状疗效总有效率、不良反应发生率和成本-效果比。[结果]试验组和对照组的Hp根除率分别为71.05%和75.00%(P〉0.05),临床症状疗效总有效率分别为94.74%和75.61%(P〈0.05),不良反应发生率分别为5.26%和34.09%(P〈0.01),成本-效果比之差为119.18元。[结论]连芙胃和口服液联合奥美拉唑和阿莫西林是一种有效、安全和经济的根除Hp治疗方案。

关 键 词:幽门螺杆菌  根除率  中西医结合疗法  三联疗法

Randomized controlled trial of Lianfu Weihe oral solution combined with omeprazole and amoxicillin in the treatment of Helicobacter pylori infection
PAN J ie-lu,LIN Jiang,ZHU Mei-ping,LU Mei-hua. Randomized controlled trial of Lianfu Weihe oral solution combined with omeprazole and amoxicillin in the treatment of Helicobacter pylori infection[J]. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2011, 19(6): 362-365
Authors:PAN J ie-lu  LIN Jiang  ZHU Mei-ping  LU Mei-hua
Affiliation:PAN Jie-lu,LIN Jiang,ZHU Mei-ping,LU Mei-hua(Department of Gastroenterology,Shuguang Hospital,Shanghai University of TCM,Shanghai 200021,China)
Abstract:[Objective]To evaluate the efficacy,safety and cost-effectiveness of Lianfu Weihe oral solution(LWOS) combined with omperazole and amoxicillin in the treatment of Helicobacter pylori(Hp)infection.[Methods]Eighty-six Hp positive subjects were randomized into two groups:42 in test group,receiving LWOS 20ml bid,omeprazole 20mg bid plus amoxicillin 1.0 bid for 1 week;46 in control group,receiving omeprazole 20mg bid,amoxicillin 1.0 bid plus clarithromycin 0.5g bid for 1 week.Main index was H.pylori eradication ...
Keywords:H.pylori  eradication rate  integrated Chinese and western medicine  triple therapy  
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