| 生肌象皮膏对糖尿病大鼠伴肌腱损伤溃疡创面的修复作用 |
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| 引用本文： | 郭悦,张杨,孙晓雷,崔丽,张玮,李秀兰. 生肌象皮膏对糖尿病大鼠伴肌腱损伤溃疡创面的修复作用[J]. 中国中西医结合外科杂志, 2011, 17(6): 590-593. DOI: 10.3969/j.issn.1007-6948.2011.06.012 |
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| 作者姓名： | 郭悦 张杨 孙晓雷 崔丽 张玮 李秀兰 |
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| 作者单位： | 天津市天津医院骨科研究所,天津,300211 |
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| 摘 要： | 目的：比较外用生肌象皮膏与贝复济对糖尿病大鼠伴肌腱损伤溃疡创面的修复作用。方法：20只健康Wistar大鼠以链脲佐霉素溶液腹腔注射制备糖尿病大鼠模型,于大鼠腰背部脊柱两侧制作2个伴肌腱损伤的圆形溃疡创面,随机分2组,分别应用生肌象皮膏和贝复济对创面进行换药。结果：经生肌象皮膏换药治疗的大鼠,其溃疡创面面积及创面愈合率在换药后期与贝复济组相比较有明显统计学意义（P〈0.05）。结论：生肌象皮膏比贝复济更能够有效促进糖尿病溃疡创面的愈合,尤其在用药后期效果更为显著。
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| 关 键 词： | 糖尿病溃疡 链脲佐菌素 生肌象皮膏 贝复济 |
Repairing role of Myogenic Elephatis Corium Cream to Ulcer Wound with Tendon Injury Model in Diabetic Rats |
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| Guo Yue,Zhang yang,Sun Xiaolei,et al.. Repairing role of Myogenic Elephatis Corium Cream to Ulcer Wound with Tendon Injury Model in Diabetic Rats[J]. Chinese Journal of Surgery of Integrated Traditional and Western Medicine, 2011, 17(6): 590-593. DOI: 10.3969/j.issn.1007-6948.2011.06.012 |
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| Authors: | Guo Yue Zhang yang Sun Xiaolei et al. |
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| Affiliation: | Guo Yue,Zhang yang,Sun Xiaolei,et al.Tianjin Orthopaedic Hospital,Tianjin(300211),China |
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| Abstract: | Objective To compare the repairing effect of myogenic elephatis corium cream and bFGF-ESSEX on ulcer wound of diabetic rats with tendon injury.Methods Diabetic rats models were successfully established by intraperitoneal injection of streptozotocin solution,and two round ulcer surfaces combined with tendon injury were prepared on both sides of the lumbar and back spinal column. The rats were randomly divided into two groups,and myogenic elephatis corium cream and bFGF-ESSEX were separately used for dressing... |
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| Keywords: | diabetic ulcer streptozotocin myogenic elephatis corium cream bFGF-ESSEX |
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