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妥布霉素滴眼液的制备及临床观察
引用本文:杨殊力,郑永,黄长武,李立,罗凤琴.妥布霉素滴眼液的制备及临床观察[J].中国药房,2001,12(4):214-216.
作者姓名:杨殊力  郑永  黄长武  李立  罗凤琴
作者单位:重庆医科大学第二附属医院,
摘    要:目的:对我院妥布霉素滴眼液进行制备和临床疗效观察,评价其生产的可行性与确切的临床疗效。方法:77例外眼细菌性感染患者,随机分成两组,以托百士滴眼液作为阳性药物进行对照试验,参照 Gwon观察项目和计分的得分形式给予评价。结果:妥布霉素滴眼液和托百士滴眼液总有效率为92.7%和94.4%,相互对照,无显著性差异(P<0.05)。结论:妥布霉素滴眼液制备工艺简单,疗效确切,可作为医院制剂推广。

关 键 词:妥布霉素滴眼液  托百士滴眼液  制备  临床研究
文章编号:1001-0408(2001)04-0214-03
修稿时间:2000年11月9日

Preparation and Clinical Therapeutic Effect of Tobramycin Eye Drops
YANG Shuli,ZEN Yun,Huang Changwu,LI Li,LOU Fengqing.Preparation and Clinical Therapeutic Effect of Tobramycin Eye Drops[J].China Pharmacy,2001,12(4):214-216.
Authors:YANG Shuli  ZEN Yun  Huang Changwu  LI Li  LOU Fengqing
Abstract:OBJECTIVE:To assess the feasibility of production and effects of Tobramycin eye drops prepared in this hospital for treating ocular infections.METHODS: 77 patients with external ocular infections were randomly divided into two groups with imported Tobrex as control drug to compare the effects.Assessment was made according to Gwon project re-sults. RESULTS: Overall improvement rates were 92.7% in Tobramycin eye drops group and 94.4% in control group without significant difference between two groups(P> 0.05) .CONCLUSION: The technology of Tobramycin eye drops production is simple,therapeutic effect is satisfactory,and the production in hospital is feasible.
Keywords:Tobramycin eye drops  Tobrex eye drops  preparation  clinical study
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