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心房除颤电场分布仿真的电极位置与尺寸优化
引用本文:王璁,杨圣均,郑懿,邬小玫,王群山,魏大名. 心房除颤电场分布仿真的电极位置与尺寸优化[J]. 中国医疗器械杂志, 2014, 0(2): 88-93
作者姓名:王璁  杨圣均  郑懿  邬小玫  王群山  魏大名
作者单位:[1]专用集成电路与系统国家重点实验室(复旦大学),上海市200433 [2]上海交通大学医学院附属新华医院,上海市200092 [3]杭州电子科技大学计算机科学与技术学院,杭州市310018
基金项目:上海市科委重点课题攻关项目(11441901702)
摘    要:该文提出了一种基于心脏建模及有限元求解的心房除颤电场分布仿真方法,用于分析动物实验和临床验证均无法精确测量的心脏除颤电场分布,为电除颤方法研究提供工具。该研究使用包含完整的心房解剖结构的心脏模型,采用有限元方法进行求解;并设计了由除颤电压阈值、高场强率、除颤能量阈值三个参数组成的评价指标体系评价除颤效果。对经静脉房颤除颤时不同电极位置与尺寸的心脏电场分布进行了仿真研究,结果与文献报道有相当好的吻合度,初步验证了该方法的可行性。

关 键 词:心房颤动  心内膜低能量除颤  有限元  电场分布仿真

Optimization of Electrode Location and Size on Simulation in Electric Field Distribution of Atrial Deifbrillation
Wang Cong,Yang Shengjun,Zheng Yi,Wu Xiaomei,Wang Qunshan,Wei Daming. Optimization of Electrode Location and Size on Simulation in Electric Field Distribution of Atrial Deifbrillation[J]. Chinese journal of medical instrumentation, 2014, 0(2): 88-93
Authors:Wang Cong  Yang Shengjun  Zheng Yi  Wu Xiaomei  Wang Qunshan  Wei Daming
Affiliation:1 State Key Laboratory ofASIC & System, Fudan University, Shanghai, 200433 2 Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200092 3 School of Computer Science and Technology, Hangzhou Dianzi University, Hangzhou, 310018)
Abstract:A distributed simulation method of electric field based on the atrial defibrillation of the heart modeling and finite element solution is proposed in this study. In order to solve the problem that ordinary clinical trials could not measure the actual distribution of the defibril ation electric field in the heart accurately, this method provides a research tool for electrical defibril ation. A complete atrial anatomical structure in the heart model is used in the research, the finite element method is proceeded to solve; Three parameters: defibril ation threshold voltage, the high field strength rate and the defibril ation threshold energy are set to evaluate the effect of defibril ation. The heart electric field distributions of transvenous atrial defibril ation with different electrode locations or sizes are simulated. The simulation results and the reported results match fairly wel , which initial y verify the feasibility of this method.
Keywords:atrial fibril ation  low-energy endocardia defibril ation  finite element  electric field distribution simulation
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