温州地区儿童肾小球疾病流行病学特点和438例病理回顾性分析

目的：研究温州地区儿童肾小球疾病流行病学特点及病理类型分布状况。方法：分析1996年7月至2002年6月间我院2321例小儿肾小球疾病流行病学特点。结果：原发性肾小球疾病(PGD)2013例，男：女＝1．95：1，孤立性血尿(IH)占41．8％。继发性肾小球疾病(SGD)94例中，紫癜性肾炎(PN)219例，乙肝病参毒相关性肾炎35例，两者均以男性多见，狼疮性肾炎30例，女性24例。PGD和SGD的高发年龄段均为7—14岁。在438例肾活检中，PGD322例，占73．3％；SGD 105例，占24％。轻微病变(ML）在PGD病理类型分布上占25．8％。结论：PGD为温州地区儿童最常见的肾小球疾病，男性多发，以IH最多见，病理类型分布上以ML最常见；SGD以PN最常见；7—14岁年龄段为PGD和SGD的高发人群。

Epidemiological features of children's glumerular diseases in Wenzhou prefecture and the retrospective analysis of the pathological type in 438 cases

Objective:To investigate the demographic features and the pathomorphologial types of children s glomeru-lar diseases in Wenzhou.Zhejiang, China. Methods:The demographic features of 2321 patients with glomerular diseases between July 19% and June 2002 have been analyzed in this study. Results: In 2013 patients with primary glomerular diseases (PGD),the male to female ratio is 1.95:1,isolated Hematuria(IH)accounting for 41.8%. In294 patients with secondary glomerular diseases( SGD), purpura Nephritis(PN) accounting for 74.5% .Of 438 patients underwent pathomorphologial type analysis,minor glomerular abnormalities(ML)accounting for 25.8%. Conclusion:PGD is the most common form of children' s glomerular diseases in Wenzhou. Male patients predominate. IH is the most common form of PGD, ML is the most common form of PGD in pathomorphologial types. PN is the most common form of SGD. Patients aged 7 - 14 account for the highest percentage both in PGD and SGD.