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硝酸异山梨酯加强心利尿药治疗充血性心力衰竭97例
引用本文:丁世芳,苏林青,马大波.硝酸异山梨酯加强心利尿药治疗充血性心力衰竭97例[J].中国新药与临床杂志,1993(2).
作者姓名:丁世芳  苏林青  马大波
作者单位:广州军区武汉总医院,广州军区武汉总医院,广州军区武汉总医院 武汉 430070,武汉 430070,武汉 430070
摘    要:本文对236例充血性心力衰竭患者的治疗进行回顾性分析。发现其中采用地高辛加氢氯噻嗪对照组139例者(男102例,女37例;年龄44±10a)与上述药物基础上再加用硝酸异山梨酯10mg/次,每日3-6次者治疗组97例(男73例,女24例;年龄47±10a)比较,2组疗程均≥3wk。发现加用硝酸异山梨酯组心衰程度改善明显优于未加用组(P<0.01)。

关 键 词:硝酸异山梨酯/治疗应用  充血性心力衰竭/药物疗法  心脏功能试验  联合药物疗法

Isosorbide dinitrate combined cardiotonics and diuretic for treatment of congestive heart failure in 97 patients
DING Shi-Fang,SU Lin-Qing,MA Da-Bo.Isosorbide dinitrate combined cardiotonics and diuretic for treatment of congestive heart failure in 97 patients[J].Chinese Journal of New Drugs and Clinical Remedies,1993(2).
Authors:DING Shi-Fang  SU Lin-Qing  MA Da-Bo
Abstract:The 236 patients with congestive heart failure were divided into 2 groups: (A) 139 patients(M 102, F 37; age44 ± 10 a)were treated with digoxin 0.125-0.25 mg qd or bid and hydrochloro-thiazide 50-100 mg qd po; and(B) 97 patients(M 73, F 24; age 47± s 10 a)were given isosorbide dinitrate 10 mg, 3-6 times/d in addition. The courses of treatment were ≥ 3 wk in both groups. The results showed better cardiac functions and lower heart failure scores in group B than group A.
Keywords:is1osorbide dinitrate/therapeutie use  congestive heart failure/drug therapy  heart function tests  combination drug therapy
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