| 止痛胶囊对大鼠镇痛作用的实验研究 |
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| 引用本文： | 刘延庆,朱健泉,薛永骥,郭试瑜,久光正.止痛胶囊对大鼠镇痛作用的实验研究[J].实用临床医药杂志,2000(6). |
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| 作者姓名： | 刘延庆 朱健泉 薛永骥 郭试瑜 久光正 |
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| 作者单位： | 扬州大学医学院!扬州，225001，扬州大学医学院附属医院!扬州，225001，扬州大学医学院!扬州，225001，日本昭和大学医学部!东京，142，日本昭和大学医学部!东京，142 |
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| 基金项目： | 江苏省科委立项资助项目 |
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| 摘 要： | 目的 :探讨止痛胶囊对于大鼠的镇痛作用及其机理。方法 :采用光热刺激鼠尾—逃避法 (Tailflicktest)测定大鼠痛阈。结果 :止痛胶囊能剂量依赖性地提高大鼠光热刺激鼠尾—逃避法的痛阈 ;纳洛酮能部分翻转止痛胶囊的镇痛作用。结论 :止痛胶囊具有镇痛作用 ,其镇痛作用可能涉及阿片受体
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| 关 键 词： | 中药 镇痛 光热刺激鼠尾-逃避法 吗啡 |
EXPERIMENTAL STUDY OF ANALGESIC EFFECT ON HAMSTER WITH ZHENTONG JIAONANG AND ITS MECHANISM |
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| LIU Yan qing,ZHU Jian quan,XUE Yong ji,GUO Shi yu,Hisamits Tadashi.EXPERIMENTAL STUDY OF ANALGESIC EFFECT ON HAMSTER WITH ZHENTONG JIAONANG AND ITS MECHANISM[J].Journal of Clinical Medicine in Practice,2000(6). |
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| Authors: | LIU Yan qing ZHU Jian quan XUE Yong ji GUO Shi yu Hisamits Tadashi |
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| Abstract: | Objective:To inquire into the analgesic effect on hamster with ZHENTONG JIAONANG (pain-alleviated capsule) and its mechanism. Method:Tail flick test was used to determinate pain thresholds of hamster.Results: ①ZHENTONG JIAONANG could raise thresholds of hamster dependently by method of tail flick test;②Naloxone could partly bend back analgesic effect of ZHENTONG JIAONANG.Conclusion:ZHENTONG JIAONANG has the analgesic effect which is probably related to opium receptor. |
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| Keywords: | chinese herbal drugs analgesia tail flick test morphine |
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