低级别胶质瘤患者脑功能区的可塑性

低级别胶质瘤是神经外科的常见疾病,其呈浸润性生长,多累及脑功能区,发病时多无神经功能障碍。目前手术切除仍是首选的治疗方案,如何在最大程度地切除肿瘤的同时保留神经功能,对神经外科医师来说仍是一项挑战。近年来发现,在低级别胶质瘤患者中,脑功能区存在较大的可塑性,并且存在着不同的功能区重构模式。对低级别胶质瘤的这种特性的研究和利用,可针对不同患者脑功能重构的不同模式调整相应的手术策略,从而提高手术切除率,降低病残率。

Brain Functional Areas Plasticity of Patients with Low Grade Glioma

Low grade glioma(LGG) is a common disease in neurosurgery,it often invades brain functional regions with infiltrative growth.Patients with LGG always have no neurological deficits when they are discovered.Nowadays operation is still the first-line treatment,how to resect the tumor in maximum extent while preserving neurological function is still an challenge to neurosurgeons.In recent years,it's found much plasticity of brain functional areas exists in patients with LGG,and the reorganization of functional regions have different models.According to this LGG's feature,the operative strategy can be adjusted based on different reorganization models of functional regions in different patients,to increase the extent of resection and decrease the morbidity.