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糖尿病周围神经病变的发病机制及中药木丹颗粒干预研究新进展
引用本文:赵步长,赵涛,赵明中. 糖尿病周围神经病变的发病机制及中药木丹颗粒干预研究新进展[J]. 中国医药导报, 2013, 10(12): 33-35
作者姓名:赵步长  赵涛  赵明中
作者单位:赵步长 (西安步长心脑血管病医院心脏科,陕西西安,710082);赵涛(天津中医药大学,天津,300193);赵明中(西安步长心脑血管病医院心脏科,陕西西安,710082);
摘    要:糖尿病周围神经病变(DPN)是糖尿病患者的常见并发症之一,其发病机制十分复杂,并发DPN严重影响患者的生活质量。在治疗方面,目前尚无特效的西药。中药木丹颗粒成分多样,对DPN有多层面的保护作用。本文就木丹颗粒对DPN的发病机制的干预及临床疗效的研究进展做一综述,为DPN的中医药综合防控策略提供依据。

关 键 词:糖尿病周围神经病变  糖基化终末产物  神经修复  木丹颗粒

New advances in the mechanism of diabetic peripheral neuropaphy and effects of Mudan Granule intervention
Affiliation:ZHA Buchong ZHA Tao ZHA Mingzhon 1.Department of Cardiology, Xi'an Buchang Cardiocerebral Vascular Disease Hospital, Shaanxi Province, Xi'an 710082, China; 2.Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Abstract:Diabetic peripheral neuropaphy (DPN) is one of the commonly complications in diabetes. It has a complex series of pathogenesis and seriously affects patients" qulity of life. No specific drug can be used to treat DPN so far. However, traditional Chinese medicine Mudan Granule has compo4nd herbal formulae which has a variety of effects on DPN. The article makes a review of the pathogenesis of DPN and effects of Mudan granules intervention in order to provide the basis for comprehensive prevention and treatment of DPNby traditional Chinese medicine.
Keywords:Diabetic peripheral neuropaphy  Advanced glycation end products  Nerve repair  Mudan Granule
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