Barrett食管的临床研究

目的:分析Barrett食管(BE)的病因、内镜下特征表现及临床病理特点,探讨BE和食管腺癌的关系.方法:分析86例BE患者的临床表现、内镜诊断及病理特点.结果:所有患者均有反流性食管炎的症状.根据症状分为四组:烧心、反酸、吞咽不利、胸骨后或剑突下痛.在内镜下可分为全周型(40例)、岛型(28例)和舌型(18例).活组织检查结果示:胃底腺型上皮35例、胃贲门交界型上皮39例、特殊型柱状上皮12例.其中不典型增生者15例,尚未发现癌变.结论:BE是反流性食管炎发展的一种结果,其诊断需内镜和活组织检查,对BE的随诊观察可早期发现食管癌.

Clinical Study of Barrett Esophagus (BE)

Objective : To investigate the relationship between BE and esophageal adenocarcinoma by(analysis) of etiology,endoscopic appearances and morphological characteristics of Barrett esophagus.Methods: Clinical manifestation,endoscopic view and histological findings of 86 patients were reviewed.Results:All(patient)s had symptoms of reflux esophagitis and were grouped into heartburn,acidic reflux,dysphagia and(retrosternal)(or substernal pain).Endoscopic view of esophagus covered patterns of circumference(40(cases),)(island)(28cases) and tongue(18cases).Histological findings of biopsy showed gastic-fundic-type epithelium(35cases),junctional-type epithelium(39cases) and specialized columnar epithelium(12cases).15 of all patients had atypical proliferation without carcinoma.Conclusion: BE is one major(complication) of reflux esophagitis and surely diagnosed with endoscope and biopsy.Such patients should be(followed) up for early(diagnosis) of esophageal carcinoma.