Multimodal prophylaxis for venous thromboembolic disease after total hip and knee arthroplasty: current perspectives |
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Authors: | LU Ning Eduardo A. Salvati |
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Affiliation: | [1]Department of Orthopaedics, Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China [2]Department of Orthopaedics, Hospital for Special Surgery and Weill Medical College of Cornell University, NewYork 10021, USA |
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Abstract: | Life-threatening in the short term and leading to a high level of morbidity in the long term, venous thromboembolism (VTE) is the most fearful complication following lower limb arthroplasty. With advances in surgical procedure, anesthetic management and postoperative convalescence have altered the risks of venous thromboembolism after total joint arthroplasty in the lower extremity.The pathogenesis of VTE is multifactorial and includes the well-known Virchow's triad of hypercoagulability, venous stasis and endothelial damage. Therefore, it is appropriate to use a multimodal approach to thromboprophylaxis. Despite extensive research, the ideal multimodal prophylaxis against venous thrombolism has not been identified. So this article reviews the recent developments in multimodal prophylaxis for thromboembolism after total joint arthroplasty. |
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Keywords: | Venous thromboembolism Arthroplasty,replacement,hip Arthroplasty,replacement,knee |
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