超声造影时间-强度曲线分析在乳腺良恶性肿块诊断中的应用价值

目的进一步探讨超声造影结合时间-强度曲线分析在乳腺良恶性肿块鉴别诊断中的价值。方法以病理结果为标准，比较95例乳腺肿块的超声造影表现及时间-强度曲线。结果60个乳腺良性肿块的时间-强度曲线斜率、峰值强度均较35个恶性肿块小，60个良性乳腺肿块的时间-强度曲线斜率、峰值时间、峰值强度与周围组织的差值均较35个恶性肿块小与周围组织的差值，差异均有统计学意义（P〈0．05）。良性肿块的时间-强度曲线形态与周围正常乳腺组织相似，清除相有一平台期；恶性肿块的时间-强度曲线形态与周围正常组织相差较大。结论超声造影结合时间-强度曲线分析有助于乳腺良恶性肿块的鉴别诊断。

Application value of contrast-enhanced ultrasound combined with time-intensity curve analysis on breast lesions

Objective To explore the value of contrast - enhanced ultrasound combined with time-intensity analysis in differential diagnosis of breast lesions. Methods Pathologic results were regarded as golden standard. Ninety-five lesions were examined by contrast - enhanced ultrasound and time-intensity analysis. Results The time-intensity curve rate and peak value in 60 benign breast lesions were less than those in 35 malignant breast lesions, there was significant difference between the two groups （P 〈 0. 05 ）. The difference of time-intensity curve rate, peak time, peak value and surrounding tissue in 60 benign lesions was less than that in 35 malignant lesions, there was significant difference between the two groups （ P 〈 0.05 ）. The time - intensity curve of benign lesions was similar to surrounding normal tissue, while the time - intensity curve of malignant lesions was different from surrounding normal tissue. Conclusion Contrast - enhanced ultrasound combined with time - intensity curve analysis is helpful in differential diagnosis of breast lesions.