Detection and quantification of coronary artery calcification with electron-beam and conventional CT |
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Authors: | C R Becker A Knez T F Jakobs S Aydemir A Becker U J Schoepf R Bruening R Haberl M F Reiser |
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Institution: | (1) Institute of Diagnostic Radiology, Ludwig-Maximilians University Munich, Klinikum Grosshadern, Marchioninistrasse 15, D-81377 Munich, Germany, DE;(2) Department of Cardiology, Clinics of Internal Medicine, Ludwig-Maximilians University Munich, Klinikum Grosshadern, Marchioninistrasse 15, D-81377 Munich, Germany, DE;(3) Department of Medical Data Processing, Biometry and Epidemiology, Ludwig-Maximilians University Munich, Klinikum Grosshadern, Marchioninistrasse 15, D-81377 Munich, Germany, DE |
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Abstract: | To identify patients with increased risk of having coronary artery disease (CAD), electron-beam computed tomography (EBCT)
was used for years for quantifying calcifications of the coronary arteries. The first direct comparison between EBCT and conventional
CT was performed to determine the reliability of widely available conventional CT for the assessment of the coronary calcium
score. Fifty male patients with suspected CAD were investigated with both modalities, EBCT and conventional 500-ms non-spiral
partial scan CT. Scoring of the coronary calcification was performed according to the Agatston method. Forty-two of these
patients underwent coronary angiography for the assessment of significant luminal narrowing. The correlation coefficient of
the score values of both modalities was highly significant (r = 0.982, p < 0.001). The variability between the two modalities was 42 %. Mean calcium score in patients with significant coronary luminal
narrowing (n = 37) was 1104 ± 1089 with EBCT and 1229 ± 1327 with conventional CT. In patients without luminal narrowing (n = 5) mean calcium score was 73 ± 57 with EBCT and 26 ± 35 with conventional CT. Although images of the heart from conventional
CT may suffer from cardiac motion artifacts, conventional CT has the potential to identify patients with CAD with accuracy
similar to EBCT.
Received: 13 July 1998; Revision received: 11 October 1998; Accepted: 14 October 1998 |
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Keywords: | : CT Coronary disease Coronary arteriosclerosis |
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