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Role of positron emission tomography-computed tomography in non-small cell lung cancer
Authors:Pankaj Kumar Garg  Saurabh Kumar Singh  Gaurav Prakash  Ashish Jakhetiya  Durgatosh Pandey
Abstract:Lung cancer is the leading cause of cancer-related mortality worldwide. Non-small cell carcinoma and small cell carcinoma are the main histological subtypes and constitutes around 85% and 15% of all lung cancer respectively. Multimodality treatment plays a key role in the successful management of lung cancer depending upon the histological subtype, stage of disease, and performance status. Imaging modalities play an important role in the diagnosis and accurate staging of the disease, in assessing the response to neoadjuvant therapy, and in the follow-up of the patients. Last decade has witnessed voluminous upsurge in the use of positron emission tomography-computed tomography (PET-CT); role of PET-CT has widened exponentially in the management of lung cancer. The present article reviews the role of 18-fluoro-deoxyglucose PET-CT in the management of non small cell lung cancer with emphasis on staging of the disease and the assessment of response to neoadjuvant therapy based on available literature.
Keywords:Positron emission tomography  Diagnostic imaging  Neoplasm staging  Carcinoma  Non-small-cell lung cancer  Lung neoplasms
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