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中医药抑制肿瘤血管生成抗肿瘤转移的可行性探讨
引用本文:李焕荣,李秀荣.中医药抑制肿瘤血管生成抗肿瘤转移的可行性探讨[J].中西医结合学报,2007,5(4):378-382.
作者姓名:李焕荣  李秀荣
作者单位:1. 中国中西医结合杂志社,北京100091
2. 山东中医药大学附属医院肿瘤科,济南,250011
摘    要:抑制肿瘤血管生成是控制肿瘤生长和转移的重要途径之一,以肿瘤血管形成为靶点的血管生成抑制剂研究已成为当前肿瘤基础理论和临床研究的热点。本文以传统中医药理论为基础,探讨了中医药抗肿瘤血管生成抗肿瘤转移的可行性及目前中药抗肿瘤血管生成的研究进展。认为从中药中筛选开发具有抑制肿瘤新生血管生成和阻断肿瘤转移途径的新药,对于控制肿瘤侵袭、转移、改善患者预后和提高生存率具有十分重要的意义。

关 键 词:中医学  抗肿瘤药  血管生成抑制剂  肿瘤转移
文章编号:1672-1977(2007)04-0378-05

Feasibility for inhibiting tumor metastasis with Chinese herbal medicines as angiogenesis inhibitors
Huan-rong LI,Xiu-rong LI.Feasibility for inhibiting tumor metastasis with Chinese herbal medicines as angiogenesis inhibitors[J].Journal of Chinese Integrative Medicine,2007,5(4):378-382.
Authors:Huan-rong LI  Xiu-rong LI
Institution:1. Chinese Journal of Integrated Traditional and Western Medicine Press, Beijing 100091, China;2. Department of Oncology, Affiliated Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province 250011, China
Abstract:Anti-angiogenesis is one of the important ways to control tumor growth and metastasis, and searching for anti-angiogenesis herbs targeting tumor angiogenesis has become a hot topic in both basic and clinical research for tumor. Utilizing the traditional Chinese medicine theory, authors of this article discussed the feasibility and research of anti-angiogenesis effect of Chinese medicine on tumor. To develop new drugs inhibiting tumor angiogenesis from the Chinese native herbal medicine has an extremely vital significance in blocking tumor invasion and metastasis, as well as improving the patients' prognosis and their survival rates.
Keywords:traditional Chinese medicine  antineoplastic agents  angiogenesis inhibitors  neoplasm metastasis
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