高血压合并糖尿病的相关危险因素分析

目的:了解高血压患者中糖尿病的患病情况及其危险因素。方法:采用整群抽样方法,抽取南京市建邺区、徐州市沛县、南通市海安县、淮安市涟水县的174个村(社区)进行高血压患者筛查,共筛查出高血压患者10 431例,对高血压患者进行问卷调查及体格测量,应用Logistic回归分析高血压患者发生糖尿病的危险因素和保护因素。结果:高血压人群中糖尿病患者的比例为9.25%。Logistic回归分析显示高密度脂蛋白胆固醇偏高是高血压合并糖尿病的保护因素,OR值为0.711(95%CI:0.570～0.888);甘油三酯偏高、总胆固醇偏高、高密度脂蛋白胆固醇偏低、年龄偏大、文化程度较高、高体质指数是高血压合并糖尿病的危险因素,OR值分别为1.917(95%CI:1.663～2.209)、2.549(95%CI:2.147～3.206)、1.370(95%CI:1.059～1.772)、1.211(95%CI:1.108～1.324)、1.162(95%CI:1.054～1.281)、1.264(95%CI:1.153～1.386)。结论:重视超重或肥胖、甘油三酯偏高、总胆固醇偏高、高密度脂蛋白胆固醇偏低、文化程度较高的高血压患者糖尿病的预防,以降低高血压合并糖尿病的发病风险,提高高血压患者的生活质量。

Analysis on risk factors related to hypertension with diabetes mellitus

Objective:This study was aimed to explore the risk factors related to hypertension with diabetes mellitus. Methods:Based on logistic regression through a survey with questionnaires and physical measurement,10431 cases with hypertension were conducted. All these cases were screened from 174 villages and cluster sampled in Jianye District in Nanjing,Peixian County in Xuzhou,Haian Country in Nantong and Lianshui County in Huaian. Results:In hypertension cases,the proportion of diabetes is about 9.25%. According to logistic regression analysis,high level of high-density lipoprotein -cholesterol (HDL-C)protected the hypertension patients against diabetes,with odds ratio(OR)=0.711(95%CI:0.570~0.888);as well as triglycerides(TG),total cholesterol(TC),low level of HDL-C,age,education,high BMI were the risk factors inducing hypertension with diabetes,with OR of 1.917 (95%CI:1.663~2.209),2.549(95%CI:2.147~3.206),1.370(95%CI:1.059~1.772),1.211(95%CI:1.108~1.324),1.162(95%CI:1.054~1.281),1.264 (95%CI:1.153~1.386),respectively. Conclusion:It is concluded that overweight and obesity,high level of TG and TC,low level of HDL-C and education level are the risk factors for the hypertension cases with diabetes. Therefore,these factors must be paid more attention in hypertension control and prevention in order to decrease the risk of complicated diabetes and to elevate the quality of life for hypertension cases.