| 影响小儿急非淋白血病化疗长期缓解的因素探讨 |
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| 引用本文： | 刘志刚,束玉萍,卢宝玉,杨小葱. 影响小儿急非淋白血病化疗长期缓解的因素探讨[J]. 中国小儿血液与肿瘤杂志, 1996, 0(4) |
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| 作者姓名： | 刘志刚 束玉萍 卢宝玉 杨小葱 |
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| 作者单位： | 西安医科大学第一临床医学院，西安医科大学附设卫校儿科 |
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| 摘 要： | 使用ＨＯＡＰ＋ＤＥＡ方案治疗小儿急性非淋巴细胞性白血病（ＡＮＬＬ）３６例。２１例（５８％）先后放弃治疗。１９例坚持治疗者，完全缓解（ＣＲ）１１例（５７％），持续完全缓解（ＣＣＲ）＞５年１例（５．３％），≥２年３例（１５．８％），＞１年者２例（１０．６％）。总结认为，影响小儿ＡＮＬＬＣＣＲ最主要取决于初治时化疗强度、ＣＲ后的治疗措施，及地区经济因素。
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| 关 键 词： | 白血病，髓细胞性，药物疗法，联合，三尖杉酯碱类 |
STUDY ON AFFECTING FACTORS OF LONG-TERM REMISSION IN CHILDREN ACUTE NONLYMPHOBASTIC LEUKEMIA CHEMOTHERAPY |
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| Abstract: | Abstract: Thirty-six children with acute nonlymphobastic leukemia (ANLL) were treated withHOAP (Homoharringtonin, VCR, Ara-c, prednison plus DEA (DNA, Ara-c, VP16) regimen. Twenty-one cases in 36 gave up continuous treatment. The other 19 cases insist onstrong combined chemotherapy. The results were that: (1) the complete remission rate(CR)was 57%; (2)the ratof contining complate remission (CCR)for 5. 2. and 1 years wereseparately 5. 3% ,15. 8%and 10. 6%. Our data demonstrated: affecting children ANLL forCCR depended on mostly the strength of chemotherapy in initial stage, the method of treatment after CR, and this region of economic conditions. |
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