| 鼠皮炎湿疹模型建立的研究进展 |
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| 引用本文： | 许宗严,吴铁,吴志华. 鼠皮炎湿疹模型建立的研究进展[J]. 中国临床药理学与治疗学, 2005, 10(7): 730-733 |
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| 作者姓名： | 许宗严 吴铁 吴志华 |
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| 作者单位： | 广东医学院药理教研室,附属医院皮肤性病研究所,湛江,524023,广东 |
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| 摘 要： | 皮炎湿疹是常见的变应性炎症性皮肤病,病因复杂,建立动物模型对于探讨疾病发病机制及防治具有重要意义。近年来报道的鼠皮炎湿疹模型大致可分为变态反应性接触性皮炎及慢性皮炎湿疹模型、光变态反应性皮炎模型与特应性皮炎模型三类。造模方法多样,各有特点,适用于不同的研究方向。
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| 关 键 词： | 皮炎 湿疹 动物模型 方法评价 |
| 文章编号： | 1009-2501(2005)07-0730-04 |
| 收稿时间： | 2005-04-29 |
| 修稿时间： | 2005-06-13 |
Progress in animal model of dermatitis and eczema |
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| XU Zong-yan,WU Tie,WU Zhi-hua. Progress in animal model of dermatitis and eczema[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2005, 10(7): 730-733 |
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| Authors: | XU Zong-yan WU Tie WU Zhi-hua |
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| Affiliation: | XU Zong-yan,WU Tie,WU Zhi-huaDepartment of Pharmacology,Institute of Dermato-venerology,Guangdong Medical College,Zhanjiang 524001,Guangdong,China |
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| Abstract: | Dermatitis and eczema are allergic relapsing inflammatory skin disorders. The precise mechanisms still are unclear. Experimental animal models are indispensable tools to study the pathogenic mechanisms and test novel therapy. A considerable number of mouse models have been proposed and used to study specific aspects of the disease. This paper summarizes the currently available animal models. |
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| Keywords: | dermatitis eczema animal model method assessment |
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