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他汀类药物治疗脓毒血症的进展
引用本文:李秀华,穆心苇. 他汀类药物治疗脓毒血症的进展[J]. 国外医学:内科学分册, 2007, 34(2): 116-118
作者姓名:李秀华  穆心苇
作者单位:南京医科大学附属南京第一医院,江苏,南京,210006;南京医科大学附属南京第一医院,江苏,南京,210006
摘    要:他汀类药物是临床上常用的一种降血脂药物,此外,它还具有抗炎、改善内皮细胞的功能、调节免疫功能,近年来研究发现,他汀类药物对脓毒血症有着重要的影响,它可以抑制炎症因子的释放,抑制炎症细胞的黏附,降低脓毒血症的发生率和病死率,本文对这一领域的最新进展作一综述.

关 键 词:他汀类药物  脓毒血症  炎症因子
文章编号:1004-2369(2007)02-0116-03
修稿时间:2006-07-252006-10-28

Recent progress of statin in treatment of sepsis
LI Xiu-hua,MU Xin-wei. Recent progress of statin in treatment of sepsis[J]. Foreign Medical Sciences(Section of Internal Medicine), 2007, 34(2): 116-118
Authors:LI Xiu-hua  MU Xin-wei
Affiliation:The First Affiliated Hospital, Nanjing Medical University, Nanjing 210006, China
Abstract:Statins are effective lipid-lowering agents used extensively in medical practice. They also have antiinflammatory and immunomodulatory properties. Moreover, statins improve endothelial function. Recent studies found that statins play a very important role in sepsis. They not only inhibit the release of inflammatory factors and decrease adhesion of inflammatory cells, but also reduce the incidence of sepsis and the sepsis-related death. This article summarized the advances in the studies on the statins applied to treat sepsis.
Keywords:Statin   Sepsis   Inflammatory factor
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