Influence of the thyroid upon the glycosaminoglycans in the salivary glands in the rat |
| |
| Authors: | J A Kofoed A B Houssay H M Curbelo A A Tocci H G Gamper A C Barcelo |
| |
| Institution: | Department of Physiology, Schools of Medicine and Dentistry, University of Buenos Aires, Argentina |
| |
| Abstract: | The glycosaminoglycans of the salivary glands were studied in male rats 2 months after radiothyroidectomy, and after the daily administration of 0.1 and 1.0 μg of sodium-1-triiodothyronine to radiothyroidectomized rats for 1 month. Total uronic acid concentration was determined in the salivary glands. Chromatographie separation of the uronic acid fractions was performed on cellulose microcolumns. Radiothyroidectomy increased and the administration of triiodothyronine decreased the uronic acid concentration in the submandibular glands. These changes occurred only in the hyaluronic acid and glycoprotein fractions. No changes in uronic acid concentration were detected in the retrolingual and parotid glands. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
