电针对重症急性胰腺炎患者胃肠功能障碍及炎症因子的影响

目的]观测电针刺激对重症急性胰腺炎患者胃肠功能障碍及炎症因子的影响。方法]本次试验共纳入患者38例，将试验病例随机分为电针组和对照组，对照组常规治疗，电针组在对照组的基础上加用电针刺激足三里穴。lOd后观察2组患者血白介素-6（IL-6）、白介素-10（IL-10）等水平，并测定腹痛及腹胀评分等变化及首次肠鸣音、自主排便恢复时间。结果]电针组有效17例，治疗组有效16例。治疗后电针组患者血IL-10水平较对照组升高（P〈O.05），且腹痛及腹胀评分变化下降更为明显（P〈0.05），首次肠鸣音及自主排便恢复时间也较对照组短（P＜0.05）。结论]电针刺激可能增加血IL-10水平以抑制炎症反应，并促进胃肠功能的恢复，加快胃肠道通气恢复的时间，缓解症状，提高疗效。

Effects of Electro-acupuncture on Gastrointestinal Dysfunction and Inflammatory Response in Severe Acute Pancreatitis

Objective]To observe the alteration of electro-acupuncture on gastrointestinal dysfunction and inflammatory response in severe acute pancreatitis（SAP）. Methods] 38 MAP patients were randomly divided into two groups, and measured IL-6,IL-10 levels and recorded the abdominal distension score, abdominal pain score ,APACHE Ⅱ score on the first day onset and the 10th day. Results] Only 33 patients were included in the last analysis.lL-10 levels were significant higher and all scores decreased significantly. Conclusion] Electro-acupuncture can cause the increase of IL-10 to inhibit the inflammatory response,and can shorten recovery time of gastrointestinal dysfunction, relieve abdominal distension, abdominal pain and other clinical symptoms.