小牛血去蛋白提取物注射液联合高压氧治疗高血压脑出血的疗效分析

目的探讨小牛血去蛋白提取物注射液联合高压氧对高血压脑出血患者神经功能康复和预后的影响及其临床实用价值。方法参照1995年全国脑血管疾病会议修订的标准,收集80例高血压性脑出血患者,随机分为治疗组(40例)和对照组(40例);对照组给予开颅手术、控制血压、脱水降低颅内压、高压氧和胞二磷胆碱等综合治疗,治疗组在给予对照组治疗基础上应用小牛血治疗,评定两组患者神经功能评分,并进行统计学分析。结果治疗组总有效率为82.5%,高于对照组的65%,差异有统计学意义(P<0.05),2组治疗后神经功能缺损评分降低,与治疗前比较差异均有统计学意义(P<0.05);且治疗组改善情况优于对照组,差异有统计学意义(P<0.05)。结论小牛血去蛋白提取物注射液联合高压氧辅助治疗高血压脑出血疗效确切,安全性高。

Analysis of the Therapeutic Effect of the HBO Therapy Combining with Deproteinized Calf Blood Extract Injection on Patients with Hypertensive Cerebral Hemorrhage

Objective To observe the effect of hyperbaric oxygen （HBO） therapy combining with deproteinized calf blood extract injection on the neurological function rehabilitation and prognosis in patients with hypertensive cerebral hemorrhage and estimate its value of clinical application. Methods According to the standard revised in National Conference on Cerebrovascular Disease in 1995, 80 patients with hypertensive cerebral hemorrhage were collected and randomly divided into control group （n=40） and therapy group （n=40）. The control group received routine complex treatment including craniotomy operation, blood pressure control, dehydration to reduce intracranial pressure, HBO and citicoline. The therapy group received deproteinized calf blood extract injection on the basis of the control group. The neurological deficit scores were determined between two groups after treatment and statistical analysis were performed. Results The total effective rate （82.5%） of the therapy group was significantly higher than that （65%） of the control group （P〈0.05）.The neurological deficit score in the therapy group was significantly decreased after the treatment （P〈0.05）, and the improvement condition in the therapy group was significantly better than that in the control group （P〈0.05）. Conclusion The HBO therapy combining with deproteinized calf blood extract injection showed an exact therapeutic effect and a high safety on patients with hypertensive cerebral hemorrhage.