| 单子叶植物内生菌多糖抗肿瘤活性的研究 |
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| 引用本文： | 章传华,周高峰,魏继刚,曾汉清,柳懿鹏,段志国.单子叶植物内生菌多糖抗肿瘤活性的研究[J].数理医药学杂志,2007,20(4):527-529. |
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| 作者姓名： | 章传华 周高峰 魏继刚 曾汉清 柳懿鹏 段志国 |
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| 作者单位： | 武汉市第一医院泌尿外科,武汉,430022 |
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| 基金项目： | 武汉市卫生局重大科研项目 |
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| 摘 要： | 目的:研究单子叶植物内生菌多糖抗肿瘤活性。方法:用单子叶植物内生菌多糖对S-180和H22肝癌荷瘤小鼠进行体内和体外抑瘤实验,单子叶植物内生菌多糖对S-180荷瘤小鼠细胞分裂指数实验。结果:单子叶植物内生菌多糖对小鼠S-180实体瘤和H22小鼠肝癌具有抑制作用(P<0.001);单子叶植物内生菌多糖可干扰肿瘤细胞的细胞周期,抑制其分裂。结论:单子叶植物内生菌多糖具有一定的抗肿瘤活性。
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| 关 键 词： | 单子叶植物内生菌 多糖 肿瘤 |
| 文章编号： | 1004-4337（2007）04-0527-03 |
| 收稿时间： | 2007-02-22 |
| 修稿时间： | 2007-02-22 |
Study on Anti-Tumor Activity of Polysaccharides of Monocotyledons Endophyte |
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| Zhang Chuanhua, et al.Study on Anti-Tumor Activity of Polysaccharides of Monocotyledons Endophyte[J].Journal of Mathematical Medicine,2007,20(4):527-529. |
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| Authors: | Zhang Chuanhua |
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| Institution: | Department of Urological Surgery, the First Hospital of Wuhan , Wuhan 430022 |
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| Abstract: | Objective: To study the anti-tumor activity of polysaccharides of monocotyledons endophyte.Method: In vivo and in vitro anti-tumor assays of polysaccharides of monocotyledons endophyte were performed in S-180 and H22 liver cancer bearing mice.And the cell division index was determined in S-180 mice.Results: Polysaccharides of monocotyledons endophyte had anti-tumor effect on S-180 solid tumor and H22 liver cancer in mice(P <0.001).It also could interfere with cell cycle of tumor and inhibit cell division.Conclusion: Polysaccharides of monocotyledons endophyte has certain anti-tumor activity. |
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| Keywords: | monocotyledons endophyte polysaccharides tumor |
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