9例甲型副伤寒并发严重肾损害的临床分析

目的探讨甲型副伤寒(简称甲副)并发严重肾损害的临床特征、早期诊断思路及治疗措施。方法回顾性总结病例资料。结果中毒、消化道症状及尿检(尿蛋白、血尿等)轻度异常出现早,并随病情进展逐渐加重,泌尿系症状及氮质血症多见于极期;4例早期经抗生素治疗者病情轻,恢复快。结论甲副可导致严重肾损害,早期症状缺乏特异性,但尿检轻度异常不能忽视,为早期诊断提供依据;早期联合使用非肾毒性抗生素是避免和减轻严重肾损害的关键。

Nine patients with paratyphoid fever A complicated with severe kidney damage

Objective To study the clinical characteristics,diagnosis,and treatment of paratyphoid fever A (fever A) complicated with severe kidney damage. Methods The data were retrospectively reviewed.Results The symptoms of poisoning and gastrointestinal symptoms as well as the slightly abnormal urinalysis (proteinuria, hematuria) appeared early, which got worse along with the progression of the disease. The symptoms of urinary system and azotemia appeared in the worst period. After treatment with antibiotic, 4 patients recovered early.Conclusion Paratyphoid fever A can cause severe kidney damage, with non-specific symptoms at the early stage. The seriousness of the abnormal of urine test can't be ignored as those provides the basis for the early diagnosis. The early use of antibiotic is the key to avoid and lessen the serverity of kidney damage.