卵巢转移性肿瘤37例临床与病理分析

目的 分析和总结卵巢转移性肿瘤的临床和病理特征.方法 回顾广西壮族自治区人民医院近6年间手术治疗的卵巢转移性肿瘤共37例,分析其病理形态、免疫组织化学等病理学特征和临床资料.结果 卵巢转移性肿瘤发病年龄15~69岁,平均年龄43.6岁.临床表现为非特异性,多以附件包块伴有腹水为主要特征,占45.9%（17/37）,癌细胞检出率高达64.7%（11/17）.双侧卵巢发生有24例,占64.9%（24/37）.临床误诊率高达59.5%（22/37）.肿瘤组织形态多数以印戒细胞癌和腺癌结构为主要表现.来源部位胃肠道肿瘤占75.6%,子宫内膜样腺癌占16.2%.结论 卵巢转移性肿瘤以胃肠道肿瘤转移最为常见,确诊需病理特征与临床资料相结合.女性胃肠癌手术史者,需密切随访,警惕卵巢转移性肿瘤的发生.

Clinical and pathological analysis of 37 cases of metastatic ovarian tumors

Objective To analyze and summarize the clinical and pathological features of metastatic ovarian tumors. Methods A total of 37 cases of metastatic ovarian tumors that has treated in the Guangxi Zhuang Autonomous Region People＇s Hospital, in the past six years, were reviewed to analyze the clinical data, the morphological and immunohistological features of the metastatic ovarian tumor. Results The age of onset was from 15 to 69 years, with a mean age of 43. 6 years. Clinical manifestations are non-specific, the adnexal mass with ascites was the main feature, accounting for 45.9% （ 17/37）, and cancer cell detection rate was 64.7% （ 11/17 ）. Tumor of both ovaries was found in 24 cases, accounting for 64.9% （24/37）. Twenty-two cases of clinical ovarian tumors （ being consid- ered as the primary tumor） admitted to hospital,with clinical misdiagnosis rate as high as 59.5% （22/37）. Tumors form mainly presented as the structure of signet ring cell carcinoma and adenocarcinoma. Source areas ： gastrointesti- nal tumors accounted for 75. 6% , endometrial ad accounted for 16.2%. Conclusion Metastatic ovari- an tumor was mainly originated from gastrointestinal tumors. Its the final diagnosis depends on pathological features and clinical data. For the female with history of gastrointestinal cancer surgery, a close follow-up must be performed, a- lerting to the occurrence of ovarian metastasis.