呼吸道耐甲氧西林金黄色葡萄球菌耐药临床分析

目的了解呼吸道耐甲氧西林金黄色葡萄球菌（MRSA）感染现状及耐药性。方法选择2010—11～2011-10门诊及住院患者呼吸道标本培养的263株金黄色葡萄球菌进行分析。结果MRSA分离率为57．79％（152／263），药敏显示MRSA对万古霉素及利奈唑胺敏感，对复方新诺明及利福平保持一定敏感性，对β-内酰胺类、喹诺酮类、大环内酯类、氨基糖苷类耐药率在80％以上。结论呼吸道MRSA多重耐药情况严重，应首选万古霉素或利奈唑胺。

Analysis of drug resistance of MRSA from respiratory tract

Objective To understand the infection situation and drug resistance of MRSA from respiratory tract. Methods A total of 263 isolates of staphyloccus aureus from respiratory tract in outpatients and inpatients in Daqing oilfield general hospital from Norember 2010 to October 2011 were analyzed. Results MRSA accounted for 57.79% （ 152/263 ）, drug sensitivity result showed that MRSA was sensitive to vancomycin and linczolid and was telatively sensitive to compound sinomin and rifampicin and the resistance rates of MRSA to 13-1actam antibiotics, quino- lanes, macrolides,aminoglycosides were more than 80%. Conclusion MRSA are highly resistant to multiple antibi- otices, either vancomycin or linezolid should be chosen firstly.