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| 正交设计法优化白芷的超声提取工艺 | |
| 引用本文： | 董芙蓉,刘强,陈志良.正交设计法优化白芷的超声提取工艺[J].齐鲁药事,2011,30(5):249-251. |
| 作者姓名： | 董芙蓉 刘强 陈志良 |
| 作者单位： | 1. 广州星群(药业)股份有限公司,广东,广州,510288;南方医科大学南方医院药剂科,广东,广州,510515 2. 南方医科大学中医药学院,广东,广州,510515 3. 南方医科大学南方医院药剂科,广东,广州,510515 |
| 基金项目： | 芷冰鼻腔给药生物粘附干粉剂的临床前研究(2008B030301141)广东省科技计划项目 |
| 摘 要： | 目的优选超声法提取白芷的最佳工艺。方法采用正交设计法优化超声法提取白芷的工艺,以欧前胡素和异欧前胡素的总含量为考察指标,超声时间、加醇量、乙醇浓度作为考察的因素,各取三个水平,分别为超声时间15 min、30 min、45 min;加醇量9倍,12倍,15倍;乙醇浓度70%,80%,90%。结果选取的最优工艺条件为:12倍量80%的乙醇超声45min提取白芷。结论影响白芷提取的最主要因素为超声时间和加醇量。 |
| 关 键 词： | 白芷 欧前胡素 异欧前胡素 超声 正交 |
Optimization of ultrasonic extraction technology of Radix Angelicae dahuricae by orthogonal experiments |
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| DONG Fu-rong,LIU Qiang,CHEN Zhi-liang.Optimization of ultrasonic extraction technology of Radix Angelicae dahuricae by orthogonal experiments[J].qilu pharmaceutical affairs,2011,30(5):249-251. | |
| Authors: | DONG Fu-rong LIU Qiang CHEN Zhi-liang |
| Institution: | DONG Fu-rong1,3,LIU Qiang2,CHEN Zhi-liang3(1.Guangzhou Xingqun Pharmaceutical Co.,Ltd.,Guangzhou 510288,China,2.College of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,3.Department of Pharmacy,Nanfang Hospital Affiliated to Southern Medical University,China) |
| Abstract: | Objective To optimize the extraction technology of Radix Angelicae dahuricae by ultrasonic method.Methods Orthogonal design was taken to optimize extraction technology by ultrasonic method.Total content of imperatorin and isoimperatorin were taken as investigation index.Ultrasound time,amount and concentration of ethanol were taken as investigation factors.Ultrasound time of 15 min,30 min and 45 min were taken respectively as three different levels,amount of ethanol were 9 times,12 times and 15 times;Concen... |
| Keywords: | Radix Angelicae dahuricae Imperatorin Isoimperatorin Ultrasound method Orthogonal experiments |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |