维奥欣治疗冠心病心绞痛56例疗效观察(附消心痛30例)

目的:观察维奥欣抗心绞痛疗效,改善缺血性心电图及降脂作用。方法:治疗组(维奥欣组)56例,男34例,女22例,年龄58±5岁,给维奥欣160mg/次,1日3次,疗程6周;消心痛组30例,男性17例,女性13例,年龄57±6岁,给消心痛10mg/次,1日3次,疗程6周。结果:①治疗组抗心绞痛显效率51.8%,对照组53.3％(P>0.05)。②治疗组心电图改善总有效率35.7％,对照组36.7(P>0.05)。③治疗组降低血胆固醇(TC)和甘油三酯(TG)的总有效率为82.9％和80.6％;消心痛组分别为14.6％和15.4％。④维奥欣无任何毒副作用,临床使用安全。结论:维奥欣在抗心绞痛,改善缺血性心电图方面与消心痛相似,但维奥欣是一个安全、有效的降脂药物,特别适用于高脂血症合并冠心病的治疗。

The Effect Observation of Weiaoxin in Treating Coronary Heart Disease and Angina Pectoris in 56 Cases

To observe the efficacy of weiaoxin for angina Pectoris, and also the action of it for improving ischemic EGG and reducing lipoid.Method: treatment group(weiaoxin group)56 patients,M34,F22(58+ 5)were treated with weiaoxin in a dose of 160mg t. i. d for 6 weeks and comparison group(Isosorbide dinitrate tablets group) :30 patients M17, F13(57 + 6 ) were treated with Isosorbide dinitrate tablets in a dose of 10mg t.i.d for 6 weeks, too. Result:1 As the comparison result showed that the effective rate in the treatment group was 51.8% .and the comparison group was 53.3%(P>0.05).2the ECG effective rate in the treatment group showed 35.7% . and comparison group was 36.7%(P>0.05); 3The total effective rate of the treatment group in reducing Cholesterol (Tc) and hyperglyceridemia (TG) was 82.9% and 80.6%, Isosorbide dinitrate tablets group was 14.6% and 15.4% ;4 There is no adverse reactions found in weiaoxin.So it is a safe drug for medication Conclusion: :There is something similar between weiaoxin and Isosorbide dinitrate tablets in antagonizing angina pectoris and in improving ischemic ECG. but the most important thing is that weiaoxin is a kind of safe, effective lipoid-reducing medicine, it is especially fit for the treatment of hyper-lipoidemia with coronary heart disease.