| 染色体介导AmpC B-内酰胺酶表达的分子调控机制的研究进展 |
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| 引用本文： | 赵付菊.染色体介导AmpC B-内酰胺酶表达的分子调控机制的研究进展[J].检验医学,2014(10):1064-1068. |
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| 作者姓名： | 赵付菊 |
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| 作者单位： | 复旦大学附属华东医院检验科,上海,200040 |
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| 基金项目： | 中央保健委员会资助项目(B2009B042)；上海市科学技术委员会资助项目 |
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| 摘 要： | 细菌产生β-内酰胺酶引起临床抗感染治疗的失败已成为全球性的医疗保健问题,AmpC β-内酰胺酶（简称AmpC酶）是其中重要的-种,有关其诱导表达的分子机制的研究日渐更新,现就AmpC酶染色体介导的调控机制的研究现状进行综述.
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| 关 键 词： | AmpC β-内酰胺酶 染色体介导 分子调控 |
Research advancement in the molecular regulation mechanism on the expression of chromosomally-mediated AmpC beta-lactamase |
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| ZHAO Fuju,ZHAO Hu.Research advancement in the molecular regulation mechanism on the expression of chromosomally-mediated AmpC beta-lactamase[J].Laboratory Medicine,2014(10):1064-1068. |
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| Authors: | ZHAO Fuju ZHAO Hu |
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| Institution: | ZHAO Fuju, ZHAO Hu. (Department of Clinical Laboratory, Huadong Hospital, Fudan University, Shanghai 200040, China) |
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| Abstract: | Bacterial resistance to beta-lactamase antibiotics through producing beta-lactamase has become a worldwide healthy care problem AmpC beta-laetamase （AmpC） is a major one of beta-laetamases. Extensive research has focused on the molecular regulation meehanism pertaining to induction. The recent researches on the regulation meehanism about the expression of ehromosomally-mediated AmpC are reviewed. |
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| Keywords: | AmpC beta-lactamase Chromosomal mediation Molecular regulation |
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