嘉兴市儿童肺炎支原体IgM抗体结果分析

目的分析嘉兴市儿童肺炎支原体（MP）感染规律，为临床早期诊断、早期治疗提供依据。。方法采用酶联免疫吸附测定法（ELISA）法，对2011年12月至2012年11月间在嘉兴市第二医院就诊的0～12岁吸道感染患儿2275例进行肺炎支原体免疫球蛋白M抗体（MP—IgM抗体）检测，并分析〈1岁、l～6岁和～12岁年龄组及全年4个季度患儿MP—IgM抗体的阳性检出率。结果2275例呼吸道感染患儿，栓出MP—IgM抗体阳性295例，阳性率为12．97％，其中〈1岁、1～6岁和一12岁年龄组患儿MP—IgM抗体阳性检出率分别为8．88％（30／338）、13．67％（205／1500）和13．73％（60／437）；1岁以内患儿MP—IgM抗体阳性率均低于其它两个年龄组，差异具有统计学意义（∥值分别为5．673和4．371，均P〈0．05），1～6岁和～12岁两组比较差异无统计学意义（／=0．001，P〉0．05）。4个季度阳性检出率分别为14．44％（65／450）、12．36％（83／671）、9．82％（40／407）和14．20％（107／747），差异均有统计学意义（，=10．462，P〈0．05）。结论MP感染的患儿以学龄前儿童及学龄期儿童为主，一年四季均可发病，第3季度最低，第一、第4季度较高。

Mycoplasma pneumoniae-IgM antibody children in Jiaxing City

Objective To analyze the ligatures of mycoplasma pneumoniae （MP） in children in Jiaxing so as to provide basis for early diagnosis and treatment. Methods Enzyme-linked immunosorbent assay （ELISA） method was used to detect MP IgM antibody in 2 275 infected cases aged 0 - 12 years old admitted in the Second Hospital of Jiaxing during December 2011 and November 2012. The positive detection rate of three groups （group aged 〈 lyear, group aged 1 -6 years, group aged 7 - 12 years） and in four quarters were analyzed. Results Among 2 275 infected children, 295 cases were found with positive MP-IgM antibody, and the positive rate was 12.97%. The detection rate of positive MP-IgM antibody in three groups was 8.88% （30/338）, 13.67% （205/1 500） and 13.73% （60/437）, respectively. The positive rate of MP-IgM antibody of the group aged 〈 1 year was lower than the other two groups, and the difference was significant （X2 value was 5. 673 and 4. 371, respectively, both P 〈 0.05 ）. But there was no significant difference between the group aged 1-6 years and the group aged 7-12 years （X^2 = 0. 001, P 〉 0.05 ）. The positive rate of four quarters was 14.44% （65/450） , 12.36% （83/671）, 9.82% （40/407） and 14.20% （107/747）, respectively, and the ditterence among them was significant （X^2 = 10. 462,P 〈 0.05）. Conclusion Most Mp infections occur in school-aged children and preschool children. It may onset throughout the year. At the third quarter the incidence is lowest, but it is relatively high at the first and fourth quarter.