梅毒血清固定合并妊娠临床病例分析

目的探讨血清固定的梅毒患者妊娠后的治疗方法、妊娠结局。方法将42例确诊为梅毒血清固定的孕妇分为两组:治疗组23例,应用苄星青霉素,每周1次肌内注射,连续3周,孕早期3个月和晚期3个月各治疗一疗程。非治疗组19例,全程未用抗梅毒药物治疗。结果治疗组早产1例,无死胎、死产现象,先天性梅毒患儿1例;非治疗组早产2例,无死胎,先天性梅毒患儿4例,两组出生先天性梅毒患儿比较,差异有统计学意义(P<0.05)。结论血清固定的梅毒患者建议进行规范的抗梅毒治疗,能改变妊娠结局,预防先天梅毒儿的发生。

Clinical Analysis of Pregnancy Cases Accompanied by Sero-resistance Syphilis

Objective To analyze the treatment of pregnant women with sero- resistance syphilis, and investigate their pregnant outcomes. Methods Forty six pregnant women with sero-resistance syphilis were divided into two groups： the treatment group and the non-treatment group. The former were treated by Benzathine Penicillin with three weeks, once per week, repeating the treatment in the first three pregnancy month and the last three pregnancy month; the latter were totally not treated. Results There were two premature births and one congenital syphilis infant in the treatment group, and four premature births, one dead fetUs and five congenital syphilis infants in the other group. The difference has statistical significance（P〈 0.05）, by compared the two group of congenital syphilis infants. Conclusion Treating the pregnant women with sero-resistance syphilis can change the pregnancy outcomes and control the incidence of congenital syphilis infants.