扬中市2004-2009年病毒性肝炎流行趋势分析

目的分析扬中市2004-2009年病毒性肝炎流行趋势,为探讨控制措施提供依据。方法回顾性调查2004-2009年扬中市病毒性肝炎疫情资料,通过发病率线形回归模型,估计病毒性肝炎发病率的年度变化百分比（APC）。结果 6年间扬中市病毒性肝炎中甲型、乙型和未分型肝炎发病率呈下降趋势（均有P〈0.05）,APC分别为-61.902%、-61.864%和-57.216%。病毒性肝炎以30～59岁为发病高峰年龄（60.77%）,男、女性别比为2.75∶1,各型肝炎均以农民和工人发病为主（74.26%）,存在季节和地区分布差异。结论在重点人群中开展甲肝、乙肝疫苗的接种、加强预防接种为主导的综合性防治措施是控制甲、乙型肝炎疫情发生与流行的有效方法,同时戊肝已成为扬中市重点预防控制传染病之一,应采取综合性防治措施。

Analysis on epidemical trend of viral hepatitis during 2004 to 2009 in Yangzhong City

Objective To analyze the distribution and time trends of viral hepatitis from 2004 to 2009 in Yangzhong City,with aims to further explore the potential strategies for disease controlling and prevention. Methods The incidence of viral hepatitis from 2004 to 2009 in Yangzhong City was investigated based on the local infectious disease surveillance system,and the annual percent changes （APCs） were estimated by a linear regression of the logarithm on the incidence rates of hepatitis during the six years. Results A decreasing trend was observed for incidence of hepatitis A,hepatitis B and non-type hepatitis in Yangzhong City from 2004 to 2009. The changes of above viral hepatitis over time were statistically significant （P0.05）,with the APCs for hepatitis A,hepatitis B and non-type hepatitis were-61.902%,-61.864% and-57.216% respectively. The 30 to 59 age was the peak age （accounting for 60.77%）,ratio of male to female was 2.75：1. Types of hepatitis were mainly in farmers and workers （74.26%）. The seasonal and geographical distribution of hepatitis was variable. Conclusions The decreasing trends of the incidence of hepatitis A and hepatitis B might attribute to the vaccination being carried out among focus groups during the last six years. Integrated control measures should be taken to control hepatitis E,which is an important infectious viral hepatitis in Yangzhong City.