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Ommaya囊植入治疗结核性脑膜炎合并脑积水的临床转归观察
引用本文:张齐龙,叶琳,肖绍武,刘子林,章玉坤,李贡文,况卫丰.Ommaya囊植入治疗结核性脑膜炎合并脑积水的临床转归观察[J].中国全科医学,2011,14(36).
作者姓名:张齐龙  叶琳  肖绍武  刘子林  章玉坤  李贡文  况卫丰
作者单位:江西省胸科医院神经内科,江西省南昌市,330006
基金项目:江西省卫生厅科技计划项目(20081142)
摘    要:目的观察Ommaya囊植入治疗结核性脑膜炎(结脑)合并脑积水的临床转归。方法选取我院2005—2010年64例结脑合并脑积水患者,随机分为治疗组和对照组,各32例,治疗组行Ommaya囊植入术,术后每天行Ommaya囊穿刺抽液给药,30 d为一个疗程;对照组每周行腰椎穿刺鞘内注药2次。若两组患者脑积水仍加重则行脑室-腹腔(V-P)分流术。根据颅脑CT、MRI显示观察两组患者脑积水的改变情况;随访1年。结果治疗组中有效27例,无效5例,有效率为84.4%(27/32)。对照组分别行经腰椎穿刺鞘内注药及V-P分流术,其中有效19例,无效13例,有效率为59.4%(19/32)。两组患者有效率比较,差异有统计学意义(χ2=4.95,P<0.05)。结论结脑合并进展性、非梗阻性脑积水,经Ommaya囊植入并配合脑室抽液注药治疗,可有效控制部分患者脑积水的发展,避免V-P分流,最终获得临床治愈。

关 键 词:Ommaya囊  脑积水  结核  脑膜  预后  

The Study on the Role of Ommaya Reservoir in the Treatment of Tuberculous Meningitis Combined with Hydrocephalus and Clinical Prognosis
ZHANG Qi-long,YE Lin,XIAO Shao-wu,et al..The Study on the Role of Ommaya Reservoir in the Treatment of Tuberculous Meningitis Combined with Hydrocephalus and Clinical Prognosis[J].Chinese General Practice,2011,14(36).
Authors:ZHANG Qi-long  YE Lin  XIAO Shao-wu  
Institution:ZHANG Qi-long,YE Lin,XIAO Shao-wu,et al.Department of Neurology,Jiangxi Provincial Chest Hospital,Nanchang 330006,China
Abstract:Objective To observe the role of Ommaya reservoir in the treatment of tuberculous meningitis(TBM)combined with hydrocephalus and clinical prognosis.Methods 64 patients with tuberculous meningitis combined with hydrocephalus admitted to our hospital from 2005 to 2010 were randomly divided into treatment group and control group,with each group 32 cases.Ommaya reservoir was implanted in the patients of treatment group,who were given intrathecal puncture injection each day after operation,with 30 d being a cour...
Keywords:Ommaya reservoir  Hydrocephalus  Tuberculosis  meningeal  Prognosis  
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