| CD147与喉鳞状细胞癌侵袭和转移关系的研究 |
| |
| 引用本文： | 蒋远伟,王德生.CD147与喉鳞状细胞癌侵袭和转移关系的研究[J].福建医药杂志,2011,33(3):68-70. |
| |
| 作者姓名： | 蒋远伟 王德生 |
| |
| 作者单位： | 福建医科大学附属协和医院耳鼻咽喉科,福州,350001 |
| |
| 摘 要： | 目的 探讨细胞外基质金属蛋白酶诱导因子(extracellular matrix metalloproteinase inducer,EMMPRIN/CD147)在喉鳞状细胞癌表达及其与肿瘤侵袭和转移的关系.方法 采用免疫组织化学染色方法对36例喉鳞状细胞癌、癌旁正常黏膜组织、淋巴结,15例喉乳头状瘤、15例喉息肉标本...
|
| 关 键 词： | 喉鳞状细胞癌 CD147 侵袭 转移 |
The study of CD147 with the invasion and metastasis of laryngeal squamous cell carcinoma |
| |
| JIANG Yuan-wei,WANG De-sheng.The study of CD147 with the invasion and metastasis of laryngeal squamous cell carcinoma[J].Fujian Medical Journal,2011,33(3):68-70. |
| |
| Authors: | JIANG Yuan-wei WANG De-sheng |
| |
| Institution: | .Department of otorhinolaryngology,the Affiliated Union Hospital,Fujian Medical University,Fuzhou 350001. |
| |
| Abstract: | Objective To investigate the expression of extracellular matrix metalloproteinase inducer(EMMPRIN/CD147)in laryngeal squamous cell carcinoma,and the relationship with the invasion and metastasis of neoplasms.Methods The expression of CD147 was analyzed semi-quantitatively by immunohistochemical staining in 36 cases of laryngeal squamous cell carcinoma,para-carcinoma normal tissue,and lymph node,15 cases of laryngeal papilloma,and 15 cases of laryngeal polyp.Results The positive rate of expression was 47.2% in laryngeal squamous cell carcinoma,which was higher than in laryngeal polyp(13.3%)or in para-carcinoma normal tissue(5.6%),and was related with T stage,clinical stage and whether there was lymph node metastasis(P<0.05).Conclusion The positive expression of CD147 has relationship to the invasion and metastasis of laryngeal squamous cell carcinoma. |
| |
| Keywords: | laryngeal squamous cell carcinoma CD147 invasion metastasis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
