围手术前期应用高频鼻窦雾化吸入对鼻内镜鼻窦手术术中出血的影响

目的：探讨减少慢性鼻-鼻窦炎鼻内镜鼻窦手术术中出血的方法。方法：将确诊的403例慢性鼻-鼻窦炎患者采用随机双盲法分成高频鼻窦雾化吸入组（A组，n=137），171服抗生素，鼻窦局部喷药组（B组，n=138），口服抗生素和激素组（C组，n=128），并对三组患者在鼻内镜手术中出血进行对比分析。结果：A组与B组对比，P〉0．05，差异无统计学意义。A组与C组对比，P〈0．05，B组与C组对比，P〈0．05，差异均有统计学意义。结论：对慢性鼻-鼻窦炎患者施行鼻内镜手术，围手术前期局部应用激素优于全身应用激素，可减少术中出血，利于鼻内镜手术效果的提高。

The impact of bleeding during endoscopic sinus surgery in patients applicating high-frequency sinus aerosol inhalation

Objective：Explore the ways to reduce bleeding during endoscopic sinus surgery for Chronic nasal-sinusitis. Methods：403 patients diagnosed with chronic nasal-sinusitis were enrolled in this study. They were divided into three groups by a randomized, double-blind clinical trial. Group A： high-frequency sinus aerosol inhalation （n=137）,group B： local spray and oral antibiotics（n=138）,group C： oral antibiotics and hormones （n=128）. Analyze the difference of bleeding during endoscopic sinus surgery between them.Results： There was no difference between group A and group B （P〉O.05）, comparison of group A and group C, group B and group C, there were both difference （P〈0.05）. Conclusion： Topical application of hormones is superior to systemic application for chronic nasal-sinusitis patients before endoscopic sinus surgery, it can reduce bleeding during surgery.