The modified rankin scale to assess disability in myasthenia gravis: Comparing with other tools |
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| Authors: | Maria E. Farrugia MD DPhil Caroline Carmichael BA Bryan J. Cupka MD Judy Warder RNCST Kathryn M. Brennan MBChB PhD Ted M. Burns MD |
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| Affiliation: | 1. Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, , Glasgow, G51 4TF UK;2. Department of Neurology, University of Virginia, , Charlottesville, Virginia, USA |
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| Abstract: | Introduction: We explored the modified Rankin scale (mRS) as a tool to quantitate disability in myasthenia gravis (MG). Our aim was to correlate patients' perception of their disability with that of the care provider and determine its relationship with other MG‐related scores. Methods: We evaluated 107 MG patients at 2 neurological centers. Patients were assessed over the telephone before and after clinic visits using the 15‐item Myasthenia Gravis Quality‐of‐Life index (MG‐QOL15) and mRS. At the clinic, patients were assessed using the MG‐QOL15, MG Composite (MGC), and mRS. Results: The MG‐QOL15 correlated with the MGC, mRS, and assessors' scores of patients. Assessors' perception of disease burden was in line with that of the patients' scoring. MG‐QOL15 scores obtained over the telephone were consistent with those obtained in the clinic. Scores were generally higher in patients receiving steroids at >5 mg/day and in those receiving or seeking benefits. Conclusion: The MG‐QOL15 and mRS are useful for estimating disability in MG. Muscle Nerve 50 : 501–507, 2014 |
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| Keywords: | disability MG‐QOL15 modified Rankin scale myasthenia gravis quality of life |
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