电镜在甲状腺髓样癌诊断中的应用价值

目的 了解电镜在甲状腺髓样癌诊断中的应用价值。方法 通过对6例甲状腺髓样癌的光镜和电镜研究，结合文献分析甲状腺髓样癌的电镜诊断特点。结果 甲状腺髓样癌电镜观察要点为胞质内有大小不一的神经内分泌颗粒。结论 所观察到的结果在腺样型髓样癌与滤泡肿瘤、嗜酸细胞型髓样癌与嗜酸细胞腺瘤(癌)、玻璃样变梁状腺瘤样型髓样癌与玻璃样变梁状腺瘤的鉴别诊断中有重要价值。

Ultrastructural diagnosis of medullary thyroid carcinomas

Objective To investigate diagnostic values of electron microscopy(EM) in medullary thyroid carcinomas. Methods Six cases of medullary thyroid carcinomas were studied by light and electron microscope. Diagnosis and differential diagnosis of electron microscope were discussed. Results The main ultrastructural characteristic of the tumor was small and large secretory granules in the cytoplasm. Conclusion EM is useful in differentiating medullary thyroid carcinomas from follicular adenoma, oxyphilic adenoma/carcinoma and hyalinizing trabecular adenoma.