慢性阻塞性肺疾病患者抑郁、焦虑情绪调查

目的：发现慢性阻塞性肺疾病（COPD）病人伴抑郁、焦虑情绪的患病率，并分析其相关的影响因素。方法：对62例COPD患者进行了一般情况及医院焦虑抑郁量表（Hospital Anxiety and Depression Scale，HAD）问卷调查。结果：有抑郁情绪的患者42人（67．7％）。有焦虑情绪的患者的43人（69．3％）。14例Ⅲ级COPD患者中达到抑郁、焦虑症状肯定存在标准的均有13人，高达92．8％。Logistic多因素回归分析，男性比女性病人更易出现抑郁和焦虑症状（OR值分别为1．05，95％CI1．01-2．11，1．12，95％CI1．03-2．23），肺功能差的患者更易出现抑郁和焦虑症状（OR值分别为2．34，95％CI1．98-3．21，2．53，95％CI2．11-4．01）；对病情越了解的病人更易出现抑郁和焦虑症状（OR值分别为1．22，95％CI0．98-1．54，1．25，95％CI1．01-2．31）。结论：COPD患者中存在较高的抑郁及焦虑情绪障碍，肺功能受损程度是其主要影响因素。

Analysis of Depression and Anxiety in Patients with Chronic Obstructive Pulmonary Disease

Objective: To estimate the prevalence of depression and anxiety in patients with Chronic Obstructive Pulmonary Disease(COPD) and to analyze the possible impact factors.Methods: Sixty-two patients with COPD were measured with Hospital Anxiety and Depression Scale(HAD).Results: Fourty-two(67.7%) patients had depressive symptom,and 43 cases(69.3%) had anxiety symptom.There were 13 patients who had significant depression and anxiety symptoms from 14 patients with III-level-COPD.From logistic-regression analysis model,we found that males had more risk of depression/anxiety symptoms than females(OR 1.05,95%CI1.01~2.11,1.12,95%CI 1.03~2.23,respectively) and the risk of depression/anxiety symptoms was 2.34/2.53 times greater for patients with severe COPD than those for mild(OR 2.34,95%CI 1.98~3.21,2.53,95%CI 2.11~4.01,respectively).Meanwhile,the patients who knew more about their disease had more risk of depression/anxiety symptom than those who knew less(OR 1.22,95%CI 0.98~1.54,1.25,95%CI 1.01~2.31,respectively).Conclusion: There is a high prevalence rate of depression/anxiety symptom in patients with COPD and the degree of lung function impairment is the important impact factor.