| 壳聚糖硒抗小鼠铅中毒的作用 |
| |
| 引用本文： | 王风丹,朱连勤,张伟,王吉才,盖文婷.壳聚糖硒抗小鼠铅中毒的作用[J].微量元素与健康研究,2007,24(5):1-4. |
| |
| 作者姓名： | 王风丹 朱连勤 张伟 王吉才 盖文婷 |
| |
| 作者单位： | 1. 莱阳农学院,动物科技学院,山东,青岛,266109
2. 莱阳农学院,科技处,山东,青岛,266109 |
| |
| 摘 要： | 目的:主要研究壳聚糖硒对铅中毒小鼠的保护作用。方法:选择144只20g左右健康雌性昆明种小白鼠,随机分为6组,1组为对照组,饲喂基础日粮(自配低硒基础日粮);2组为铅中毒组,饲喂染毒饲料;3组为亚硒酸钠组,以亚硒酸钠的形式在染毒饲料中添加0.25mg/kg的硒;4～6组为壳聚糖硒组,以壳聚糖硒的形式分别在染毒饲料中添加0.125、0.25、0.5mg/kg的硒。结果:添加壳聚糖硒可明显提高小鼠的脏器指数,改善小鼠的血液中血红蛋白含量,提高小鼠的抗氧化能力,降低铅在小鼠体内的蓄积。结论:添加壳聚糖硒能明显降低铅对机体的毒性。
|
| 关 键 词： | 小白鼠 铅中毒 壳聚糖硒 拮抗作用 |
| 文章编号： | 1005-5320（2007）05-0001-04 |
| 修稿时间： | 2007-05-19 |
Resistance of Chitosan-Se on Lead Toxicity in Mice |
| |
| WANG Feng-dan,ZHU Lian-qin,ZHANG Wei,WANG Ji-cai,Gai Wen-ting.Resistance of Chitosan-Se on Lead Toxicity in Mice[J].Studies of Trace Elements and Health,2007,24(5):1-4. |
| |
| Authors: | WANG Feng-dan ZHU Lian-qin ZHANG Wei WANG Ji-cai Gai Wen-ting |
| |
| Institution: | Faculty of Animal Science and Veterinary Medicine, Laiyang Agricultural College ; Office of science and technology, Laiyang Agricultural College Qingdao Shandong 266109, China |
| |
| Abstract: | Objective:To study the protection of chitosan-se on lead toxicity in mice.Methods:144 of 20g kunming female mice were divided into six groups randomly.First group was control group.Second group was fed with lead acetate.Third group was fed with lead acetate,and added 0.25% mg/kg selenium in the from of sodium selenite.Fourth group and fifth group and sixth group also were fed with lead acetate,0.125%、0.25% and 0.5 mg/kg selenium was added in the group of 4,5,6 in the form of Chitosan-Se respectively.Result:the groups added Chitosan-Se improved the index of organs of the mice,advanced hemoglobin in blood of mice,and improved the antioxygenic property significantly,reduced the lead accumulation level in tissue and organs of mice.Conclusion:Chitosan-Secould improve lead poisoning significantly. |
| |
| Keywords: | mice lead poisoning chitosan-se antagonistic action |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
