鼻腔鼻窦内翻性乳头状瘤临床分析

报告鼻腔鼻窦内翻性乳头状瘤２１例，男１７例，女４例，男女之比为４．２５∶１。平均年龄４４．８岁，高发年龄组为３１～４０岁组，占４７．６％。最常见的临床症状是鼻阻塞，对单侧鼻腔新生物进行多部位多次活检，可在术前确诊。治疗时整块切除肿瘤和上颌窦内侧壁，可降低术后复发，本组２例经鼻内手术切除肿瘤，１９例经鼻侧切开并切除整块肿瘤及上颌窦内侧壁，其中前者１例（５０％）复发，后者４例（２１．８％）复发，总复发率为２３．８％。其中３例发生癌变，其癌变率为１４．３％。

A Clinical Analysis of Inverting Papilloma of the Nasal Cavity and Paranasal Sinuses

? A retrospective study was performed on 21 patients treat at the First Affiliated Hospital of Hubei Medical University over the fifteen years with a pathologic diagnosis of inverting papilloma of the nasal cavity and paranasal sinuses. The mean age at presentation was 44.8 years, with a male to fermale ratio of 4.25∶1. The most common symptom at presentation was nasal obstruction. Patients treated with a lateral rhinotomy and medical maxillectomy had a recurrence rate of 21.8 percent. Those treated with a less aggressive operation had a recurrence rate of 50 percent. The malignant transformation rate from inverting papilloma to squamous cell carcinoma was 14.3 percent.