| 3种常见肠杆菌科细菌耐药性变迁调查 |
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| 引用本文： | 陈孝进,彭兰. 3种常见肠杆菌科细菌耐药性变迁调查[J]. 中华医院感染学杂志, 2006, 16(1): 112-113 |
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| 作者姓名： | 陈孝进 彭兰 |
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| 作者单位： | 湖北省兴山县医疗中心,湖北,兴山县,443711 |
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| 摘 要： | 目的探讨本地区肺炎克雷伯菌、大肠埃希菌和阴沟肠杆菌的感染现状和耐药性变迁,为合理使用抗生素提供理论依据。方法用常规方法分离鉴定病原菌,用K-B法作体外耐药监测。结果3种常见肠杆菌科细菌中肺炎克雷伯菌分离率居首位,大肠埃希菌次之;5年中,3种菌对12种常用抗生素耐药率总体呈上升趋势,且产超广谱β-内酰胺酶(ESBLs)菌检出率由2000年16.5%上升到2004年32.4%,呈现上升趋势。结论临床应加强合理使用抗生素管理,控制耐药菌的产生和医院感染暴发流行。
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| 关 键 词： | 肠杆菌科细菌 超广谱β-内酰胺酶 耐药性 |
| 文章编号： | 1005-4529（2006）01-0112-02 |
| 收稿时间： | 2005-09-13 |
| 修稿时间： | 2005-11-10 |
Antibiotics Resistance Status Changing among 3 Kinds of Bacteria in Enterobacteriaceae |
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| CHEN Xiao-jin,PENG Lan. Antibiotics Resistance Status Changing among 3 Kinds of Bacteria in Enterobacteriaceae[J]. Chinese Journal of Nosocomiology, 2006, 16(1): 112-113 |
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| Authors: | CHEN Xiao-jin PENG Lan |
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| Affiliation: | Xingshan Medical Center, Xingshan, Hubei 443711, China |
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| Abstract: | OBJECTIVE To investigate the drug resistance status of Klebsiella pneumoniae,Escherichia coli and(Enterobacter cloacae) for reasonable use of antibiotics. METHODS After genus identification,drug resistance profile was analyzed by K-B method. RESULTS The predominant isolates from Enterobacteriaceae were(K.penumoniae) and E.coli.The resistant rate of the three commonly encountered bacteria in Enterobacteriaceae to antibiotics ascended yearly,with increasing isolates harboring ESBLs from 16.5%(2000) to 32.4%(2004). CONCLUSIONS Rational use of antibiotics should be obey the results of laboratory antibiotics susceptibility test to control the increasing trend and forbid outbreak of resistance. |
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| Keywords: | Enterobacteriaceae ESBLs Drug resistance |
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