| 表观遗传学与鼻咽癌 |
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| 引用本文： | 沈建军,张红雁. 表观遗传学与鼻咽癌[J]. 国际肿瘤学杂志, 2014, 0(5): 335-337 |
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| 作者姓名： | 沈建军 张红雁 |
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| 作者单位： | 安徽省立医院肿瘤放射治疗科,合肥230000 |
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| 基金项目： | 安徽省自然科学基金（1208085QH169） |
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| 摘 要： | 鼻咽癌的发病原因至今尚不十分清楚,最新的证据表明表观遗传学参与了鼻咽癌的发生发展.表观遗传学改变可以作为鼻咽癌的分子指标,有利于判断预后.针对表观遗传学改变采取干预措施未来可作为新的鼻咽癌治疗手段,并且可以开发新的鼻咽癌放疗增敏剂和新的治疗药物.研究表观遗传学在鼻咽癌中的改变,为鼻咽癌的诊断、治疗等提供了新的思路.
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| 关 键 词： | 鼻咽肿瘤 遗传 甲基化 |
Epigenetics and nasopharyngeal carcinoma |
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| Shen Jianjun,Zhang Hongyan. Epigenetics and nasopharyngeal carcinoma[J]. Journal of International Oncology, 2014, 0(5): 335-337 |
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| Authors: | Shen Jianjun Zhang Hongyan |
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| Affiliation: | ( Department of Radiation Oncology, Anhui Provincial Hospital, Hefei 230001, China) |
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| Abstract: | The etiology of nasopharyngeal carcinoma is still not very clear.Epigenetics is proved to play an important role in the occurrence and development of nasopharyngeal carcinoma （NPC）.Detection of epigenetics can serve as molecular index of NPC,and it is advantageous to the prognosis and disease of NPC.Different intervention measures in the epigenetics can be used as a new treatment of NPC,as well as the development of new NPC radiotherapy sensitization agent and new drugs.Study of epigenetics changes in nasopharyngeal carcinoma provides a new idea for the diagnosis and treatment in NPC and so on. |
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| Keywords: | Nasopharyngeal neoplasms Heredity Methylation |
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