| 癌症相关性疲劳流行病学及发病机制研究进展 |
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| 引用本文： | 陈红姗,王玉栋,刘巍.癌症相关性疲劳流行病学及发病机制研究进展[J].国际肿瘤学杂志,2014(3):187-190. |
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| 作者姓名： | 陈红姗 王玉栋 刘巍 |
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| 作者单位： | 河北医科大学附属第四医院肿瘤内科,石家庄050011 |
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| 摘 要： | 癌症相关性疲劳（CRF）是与肿瘤和（或）抗肿瘤治疗相关的疲劳，发病率高，严重影响患者生活质量。病因包括心理、生理、社会等多种影响因素，目前存在多种发病机制假说，其中炎症机制假说可能在CRF的发生、发展中发挥重要作用，多种炎症细胞因子如白细胞介素（IL）-1β、IL-6、肿瘤坏死因子-α（TNF-α）、C反应蛋白（CRP）与CRF发病显著相关。
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| 关 键 词： | 肿瘤 疲劳 炎症 细胞因子类 |
Epidemiology and pathogenesis research progress of cancer-related fatigue |
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| Chen Hongshan,Wang Yud- ong,Liu Wei.Epidemiology and pathogenesis research progress of cancer-related fatigue[J].Journal of International Oncology,2014(3):187-190. |
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| Authors: | Chen Hongshan Wang Yud- ong Liu Wei |
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| Institution: | . Department of Medical Oncology, Fourth Affiliated Hospital of Hebei Medical University, Shiftazhuang 050011, China |
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| Abstract: | Cancer-related fatigue （CRF） is associated with tumor and （or） anti-tumor treatment, which has a high incidence and seriously affects the life quality of patients. The etiology of CRF involves psychology, physiology and social factors. There are various hypothesis of pathogenesis and the inflammatory system may play an important role in the generation and development of CRF. A variety of inflammatory eytokines such as IL-1β, IL-6, TNF-α, CRP are significantly correlated with CRF. |
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| Keywords: | Neoplasms Fatigue Inflammation Cytokines |
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