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| 大剂量丙种球蛋白治疗川崎病21例疗效分析 | |
| 引用本文： | 刘艳,刘胜,杨中文. 大剂量丙种球蛋白治疗川崎病21例疗效分析[J]. 第二军医大学学报, 2003, 24(8): S008-S009 |
| 作者姓名： | 刘艳 刘胜 杨中文 |
| 作者单位： | 1. 河南科技大学第一附属医院儿科,洛阳,471003 2. 洛阳市市政工程管理处职工医院内科,洛阳,471000 3. 洛阳市中心医院儿科,洛阳,471000 |
| 摘 要： | 为探讨单剂大剂量丙种球蛋白对川崎病的疗效,对21例确诊的川崎病患儿联合应用丙种球蛋白和阿司匹林治疗,并进行疗效分析.结果表明,单剂大剂量丙种球蛋白[1 g/(kg*d)]治疗较单一阿司匹林疗效显著(P<0.05),总热程缩短(P<0.05),心电图异常发生率由23.8％降至9.5％,冠状动脉损害发生率由33.3％降至19.0％.提示单剂大剂量丙种球蛋白对川崎病患儿临床疗效显著,尤其对心血管病变有良好的防治作用. |
| 关 键 词： | 大剂量丙种球蛋白、川崎病、治疗结果 |
| 文章编号： | 0258-879X(2003)08-S8-02 |
| 修稿时间： | 2002-12-23 |
Curative effect of intravenous high dose gamma immunoglobulin in 21 children with Kawasaki disease |
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| LIU Yan ,LIU Sheng ,YANG Zhong Wen. Curative effect of intravenous high dose gamma immunoglobulin in 21 children with Kawasaki disease[J]. Former Academic Journal of Second Military Medical University, 2003, 24(8): S008-S009 | |
| Authors: | LIU Yan LIU Sheng YANG Zhong Wen |
| Affiliation: | LIU Yan 1,LIU Sheng 2,YANG Zhong Wen 3 |
| Abstract: | This study is to investigate the clinical effects of intravenous high dose of gamma immunoglobulin(IG) in treatment of Kawasaki disease(KD). A total of 21 children with KD were treated with high dose of gamma IG intravenously.The result showed that it was more effective when adding high dose of gamma IG than aspirin alone( P <0.05).The total course of fever was shortened( P <0.05);the abnormal rate of ECG decreased from 23.8% to 9.5% and rate of coronary artery impairment decreased from 33.3% to 19.0%. These results suggest that high dose of gamma IG can prevent the impairment of cardiovascular system effectively in patients with KD. |
| Keywords: | high dose of gamma globulins Kawasaki disease treatment outcome |
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