股骨近端防旋髓内钉内固定结合骨水泥填充治疗股骨转子周围转移性肿瘤

目的 分析股骨近端防旋髓内钉（PFNA）内固定结合骨水泥填充治疗股骨转子周围转移性肿瘤的疗效.方法 回顾性分析2007年6月至2013年7月应用PFNA内固定结合骨水泥填充治疗的19例股骨转子周围转移性肿瘤患者的临床资料.结果 19例患者术前视觉模拟量表（VAS）评分为（8.37±1.12）分,术后第3天VAS评分为（2.58±1.26）分,两者比较差异有统计学意义（t=22.45,P＜0.05）.Enneking评分结果显示优良率达14/19;随访期间死亡患者术后生存时间平均16.5个月;1例肾癌骨转移患者已存活64个月;术后6个月仍存活的16例患者行Karnofsky评分总有效率为13/16.结论 采用PFNA内固定结合骨水泥填充,可有效治疗股骨转子周围转移性肿瘤,能有效减轻疼痛,保存和改善患肢功能,有助于提高患者生活质量.

Proximal femoral nail antirotation and bone cement in treatment of metastatic tumors of the peritrochanteric region of femur

Objective To investigate the effect of internal fixation with proximal femoral nail antirotation （PFNA） and bone cement on peritrochanteric tumors due to metastatic carcinoma.Methods Clinical data of 19 patients with peritrochanteric tumors due to metastatic carcinoma during June 2007 and July 2013 treated with PFNA and bone cement were retrospectively analyzed.Results Visual analogue scale（VAS） was （8.37 ± 1.12） scores before surgery,and （2.58 ± 1.26） scores after 3 d surgery.There was significant difference （t =22.45,P ＜ 0.05）.Conclusion For patients with peritrochanteric tumors due to metastatic carcinoma,internal fixation with PFNA and bone cement is an effective way to relieve pain,restore and improve hmb function and enhance quality of life.