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Corticosteroid cross-reactions: an alternative view
Authors:Wilkinson S M
Institution:Department of Dermatology, The General Infirmary, Leeds, UK.
Abstract:An alternative view of corticosteroid cross-reactivity is proposed, based on 2 immune recognition sites on the corticosteroid molecule, 1 influenced by C 6/9 substitution and 1 by C 16/17 substitution. A case report is adduced in support of such a hypothesis.
Keywords:corticosteroid  cross-reaction  allergic contact dermatitis  tixocortol pivalate  hydrocortisone  budesonide  medicaments  structure-activity relationships
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