溴隐亭治疗女性高泌乳素血症并不育46例分析

目的通过对溴隐亭治疗女性高泌乳素血症并不育的临床观察,探讨高泌乳素血症临床特点及溴隐亭治疗的方法。方法观察46例高泌乳素血症并不育患者的临床表现,实施溴隐亭治疗后动态B超监测排卵及子宫内膜情况。结果46例患者经溴隐亭治疗后,血清PRL均呈不同程度下降,排卵正常者41例,占89.1%,不孕35例中,半年内妊娠者23例,占65.7%;复发性流产者11例,9例继续妊娠大于5个月,占81.8%。结论高泌乳素血症患者因表现为排卵障碍、子宫内膜异常表现、黄体功能不足等导致不孕不育,溴隐亭治疗建议配合动态B超监测排卵指导用药,妊娠后视情况缓慢减少用量,并黄体支持。

The Application of Bromocriptine for Female Hyperprolactinemia and Infertility (A Report of 46 Cases)

Objective To discuss the characteristics of hyperprolactinemia and therapy of bromocriptine through the observation. Methods 46 cases hyperprolactinemia and infertility patients were observed and monitored by B-ultrasound on ovulation and endometrial situation. Results After 46 patients were treated by bromocriptine, serum PRL reduced to different degrees, normal ovulation 41 cases, accounting for 89.1% and 35 cases of infertility, within six months of pregnancy were 23 cases, accounting for 65.7%; Recurrent abortion were 11 cases, 9 cases continued to pregnant more than five months, accounting for 81.8%. Conclusion Hyperprolactinemia patients can cause infertility due to the performance of anovulation, endometrial abnormalities performance luteal insufficiency. We should choose medicine according to Bromocriptine and B-ultrasoud.