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A double-blind,randomized, placebo-controlled,multi-center study of brofaromine in the treatment of post-traumatic stress disorder |
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| Authors: | D. G. Baker B. I. Diamond G. Gillette M. Hamner D. Katzelnick T. Keller T. A. Mellman E. Pontius M. Rosenthal P. Tucker B. A. vander Kolk R. Katz |
| Affiliation: | (1) VA Medical Center, Cincinnati, Ohio, USA;(2) VA Medical Center, Augusta, Georgia, USA;(3) VA Medical Center, Little Rock, Arkansas, USA;(4) VA Medical Center, Charleston, South Carolina, USA;(5) Dean Foundation for Health, Research, and Eduction, Madison, Wisconsin, USA;(6) VA Medical Center, Seattle, Washington, USA;(7) VA Medical Center, Miami, Florida, USA;(8) VA Medical Center, Pittsburgh, Pennsylvania, USA;(9) Behavioral Medicine Resources, New Orleans, Louisiana, USA;(10) University of Oklahoma, Oklahoma City, Oklahoma, USA;(11) Eric Lindemann Mental Health Center, Brookline, Massachusetts, USA;(12) Ciba-Geigy Corportation, Summit, New Jersey, USA |
| Abstract: | A large multi-center, double-blind, parallel trial to assess the efficacy of brofaromine in the treatment of post traumatic stress disorder (PTSD) failed to show a significant difference between the brofaromine and placebo treatment groups. The placebo response rate in this study was higher than that in previously published double-blind, placebo-controlled studies of PTSD. |
| Keywords: | Brofaromine MAOI PTSD Psychopharmacology |
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