车前番泻颗粒联合生物反馈治疗出口梗阻型便秘疗效评价

目的:评价车前番泻颗粒联合生物反馈(BF)治疗出口梗阻型便秘(OCC)的疗效。方法:66例OCC患者BF治疗一个疗程后比较治疗前后直肠压力变化,按患者意愿分为继续BF治疗组和车前番泻颗粒联合治疗组,分组治疗2月后比较2组患者临床症状改善状况。结果:BF治疗前后比较患者直肠静息压、力排结果和直肠最大耐受量显著提高(P<0.05),肛管静息压、肛门直肠缩榨压、直肠初始感觉、初始欲望、强烈欲望均无改变(P>0.05);治疗2月后,BF组和联合组患者较治疗前症状均有显著改善,且联合组优于BF组(P<0.05)。结论:BF联合车前番泻颗粒治疗方案改善患者临床症状优于单独BF治疗,是OCC的有效治疗方案。

Effective Evaluation of Biofeedback Therapy Combined with Plantain-senna Granules in Patients with Outlet Obstructive Constipation

Objective To evaluate the efficacy of biofeedback therapy combined with plantain-senna granules in treatment of patients with outlet obstructive constipation.Methods Sixty-six patients were underwent one course of biofeedback training,the change of rectal pressure before and after treatment were compared,then the patients were divided into BF group and combined group based on their own choices,the improvement of symptom were observed after treating for 2 months.Results After two weeks biofeedback training,the rectal resting pressure,force row results and maximum tolerated rectal volume were improved significantly(P<0.05).However,the anal resting pressure,anorectal squeeze pressure,as well as the initial perception,initial desire,intensive desire of rectum had no significant difference before and after treatment(P>0.05).The symptoms of patients in both group were significantly improved after treating for two months,and the efficacy of combined group was more excellent than BF group(P<0.05).Conclusion The biofeedback therapy combined Plantain-senna granules could be effectively used for treatment of outlet obstructive constipation.